The 2D:4D ratio or quotient between the index and ring finger lengths is considered a non-direct indicator of androgenisation (Schneider, Pickel & Stalla, 2006). Key words: androgenisation cortisol 2D:4D ratio autism spectrum disorders testosterone. The results indicate that the 2D:4D ratio could be used together with other parameters as an indicator of the likelihood of developing autistic traits in offspring. In addition, the severity of the symptoms of their offspring was predicted only with male parents. Although there were no differences between groups in the 2D:4D ratio, the left hand of the ASD parents showed greater predictive ability to explain empathy and autism quotients, cooperative behaviour, and cortisol levels. The sample was composed of 43 parents of offspring with ASD and 42 controls who had the 2D:4D ratio measured, answered several trait questionnaires, and had their testosterone and cortisol levels measured. This study aims to analyse if parents of people with ASD differ from the general population in several parameters of androgenisation related to the 2D:4D ratio. It has been suggested that people with autism spectrum disorders (ASD) and their parents may have highly androgenised brains, and for this reason the 2D:4D ratio is used as a marker of such idiosyncrasies. If prenatal testosterone levels in the amniotic fluid are high then the probability increases of developing lower ratio values. The 2D:4D ratio is the quotient between the index and ring finger lengths and is a non-direct indicator of androgenisation. Palabras clave: Androgenización cortisol ratio D2:D4 trastornos del espectro autista testosterona. Los resultados obtenidos indican que la ratio D2:D4 podría ser empleada, junto a otros parámetros, como indicador de la probabilidad de desarrollar rasgos autistas en los descendientes. Además, en los progenitores varones predijo la gravedad de los hijos. Aunque no se encontraron diferencias por grupo en la ratio D2:D4, la ratio de la mano izquierda de progenitores de personas con TEA mostró mayor capacidad predictiva para explicar los cocientes de empatía y autismo, conductas cooperativas y niveles de cortisol. La muestra estuvo compuesta por 43 progenitores de personas con TEA y 42 controles, de los que se midieron la ratio D2:D4, cuestionarios rasgo y niveles de testosterona y cortisol en saliva. El objetivo principal es analizar si los progenitores de personas con TEA difieren de la población general en diversos parámetros de androgenización, principalmente la ratio D2:D4. Se ha sugerido que personas con trastornos del espectro autista (TEA) y sus progenitores podrían tener cerebros altamente androgenizados, por lo que se ha utilizado como marcador de tal idiosincrasia. A mayor testosterona prenatal, incrementa la probabilidad de desarrollar una menor ratio D2:D4. La ratio D2:D4 es el cociente entre la longitud de los dedos índice y anular e indicador indirecto de androgenización. This study was financed by the Spanish Ministry of Science and Innovation (PSI2008-0448/PSIC) and the Committee for Business, Research and Science of the Regional Government of Valencia (Spain) (ACOMP/2010/250 & PROMETEO/2011/048). Ángel Romero-Martínez, Sara de Andrés-García, Patricia Sariñana-González, M.V. La ratio interdigital D2:D4 y su relación con otros indicadores de androgenización en progenitores de personas con trastornos del espectro autista What are Satiety Hormones? Find out in this link.The 2D:4D ratio and its relationship with other androgenisation parameters in parents of individuals with autism spectrum disorders.There’s a relationship between testosterone, sex, training and aggression that… continue reading.Finger length ratio (2D:4D) correlates with physical aggression in men but not in women. The association between second to fourth digit ratio, reproductive and general health among women: findings from an Israeli pregnancy cohort. Tabachnik, M., Sheiner, E., & Wainstock, T.Proceedings of the National Academy of Sciences of the United States of America, 108(39), 16289–16294. Developmental basis of sexually dimorphic digit ratios. Stay or stray? Evidence for alternative mating strategy phenotypes in both men and women. Wlodarski, R., Manning, J., & Dunbar, R. 2Nd To 4Th Digit Ratios, Fetal Testosterone and Estradiol. Lutchmaya, S., Baron-Cohen, S., Raggatt, P., Knickmeyer, R., & Manning, J.Digit Ratio (2D:4D) and Physical Performance in Female Olympic Athletes. O., Ericsson, M., Berglund, B., & Hirschberg, A. Eklund, E., Ekström, L., Thörngren, J.Those foetuses that are exposed to a higher concentration of androgens (such as testosterone) in the amniotic fluid have a lower 2D:4D ratio.
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